Mendelian randomization and transcriptome analysis reveal depression-driven regulatory patterns of the immune microenvironment in myocardial infarction and heart failure.

Front Immunol · 2026 · PMC12894390 · PMID 41694402

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hedged sentence

0.0001

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp < 0.0001actually significant

After adjusting for all covariates, PHQ-9 scores were positively and linearly associated with CVD risk; a highly significant nonlinearity was observed ( p < 0.0001).

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