DisSNPNet: Predicting disease-associated single-nucleotide polymorphisms using linkage disequilibrium, disease similarity, and 1000 Genomes Project datasets with evidence-based validation.

Biol Methods Protoc · 2026 · PMC12895193 · PMID 41696352

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a decreasing trendP = 4.088 × 10 −06actually significant

A decreasing trend was observed for higher-numbered chromosomes (Spearman’s rank correlation = −0.939, P = 4.088 × 10 −06 ), consistent with the relationship between chromosome size and SNP content.

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