Association of Immunoglobulin E With Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.

Furthermore, subgroup analysis demonstrated that serum IgE levels were markedly higher in patients with WHO functional class III heart failure compared with WHO functional class I, showing a positive trend with increasing WHO functional class (Figure 2B ). 4.

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In line with these findings, the present study demonstrated that serum IgE levels in PAH patients correlated positively with NT‐proBNP and showed an increasing trend with WHO functional class, indicating a relationship between elevated IgE and the severity of right heart failure in PAH.

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