Prognostic significance of neuroendocrine differentiation and PD-L1 expression in treatment-naïve prostate cancer.

BMC Urol · 2026 · PMC12895653 · PMID 41547728

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borderline significantno p-value reported

There was a moderate negative correlation trend between SIS and PD-L1 CPS (Spearman’s rho = -0.481, p = 0.051), indicating a borderline significant tendency where tumors with strong synaptophysin staining intensity exhibited lower PD-L1 CPS values.

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