Evaluating Adjuvant Radiation Therapy Survival Benefit in Early-Stage HER2-Positive Invasive Breast Cancer Following Breast-Conserving Surgery: A National Cohort Aligned with NRG-BR008 HERO Trial.

In the IPTW-weighted Kaplan–Meier analyses, overall survival remained consistently lower among patients who omitted RT in the adjuvant cohort, with a highly significant weighted log-rank test ( p < 0.0001) ( Supplemental Figure S2A ).

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