Barely Significant
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Timing of laparoscopic appendectomy and impacts on outcomes: A retrospective study of patients across in-hours, after-hours and holidays.

World J Gastrointest Surg · 2026 · PMC12898872 · PMID 41695843

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a positive trendno p-value reported
While perforation rates showed no significant difference, earlier surgeries demonstrated a positive trend, consistent with Drake et al [ 25 ], who reported that performing surgery within 8.6 hours helps prevent perforation.

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