Brain and circulating EV proteome signatures in schizophrenia as prognostic markers for age-related dementia.

Acta Neuropathol Commun · 2026 · PMC12905883 · PMID 41559842

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highly significantno p-value reported

2 c, our analysis demonstrated that several immune-related proteins, including C4A, HPX, JCHAIN, IGHM, and IGHG3, which were consistently dysregulated in both pathologies, displayed a strong and highly significant positive correlation with the EV-associated protein ANXA2 in bEVs.

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