miRNA profiling reveals that gga-let-7i/COL1A2 axis induces cell cycle arrest and triggers cellular senescence to accelerate ovarian aging in laying hens by suppressing the PI3K/AKT/MDM2 pathway.

Poult Sci · 2026 · PMC12906189 · PMID 41653631

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extremely significantno p-value reported

A P -value < 0.05 (denoted by a, b, c and *) and P -value < 0.01 (denoted by **) was considered statistically significant and extremely significant, respectively.

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