Establishment of a mouse model of TMAO-induced cardiac injury and application of MICT intervention.

MICT intervention alleviates cardiac dysfunction in an 8‐week TMAO‐induced mouse model of cardiac injury Relative to the TMAO group, the TMAO+MICT group exhibited a markedly significant reduction in HR, LVIDd, and LVIDs (Figure 4A,D,E ; Table S4 ; p < 0.05), along with a notable increase in both EF and LVFS (Figure 4B,C ; Table S4 ; p < 0.05).

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