Trends in colorectal cancer burden attributable to lifestyle in China (1990-2021): based on the global burden of disease study, revealing declining impact of dietary factors and rising influence of tobacco, alcohol, and obesity.

J Health Popul Nutr · 2026 · PMC12908349 · PMID 41566355

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an increasing trendno p-value reported

According to Joinpoint regression analysis, while the disease burden associated with smoking showed an overall decline from 1990 to 2021, the deceleration began to slow down from 2007 and gradually showed an increasing trend.

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a decreasing trendno p-value reported

Trends in disease burden of smoking-induced CRC, while overall showing a decreasing trend, appear to have risen in recent years (AAPC (ASMR per 100,000 population) = -0.48 (-0.54, -0.43), AAPC (ASDR per 100,000 population) = -0.54 (-0.58, -0.5)).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.