Triglyceride-glucose index demonstrates false-positive association with cardiometabolic multimorbidity progression in cardiometabolic disease patients: Observation and Mendelian randomization study.

Crucially, the sole study investigating TyG’s predictive utility across preexisting CMD statuses reported that TyG lacked predictive value for CMM progression in individuals with diabetes, while its effects were marginally significant in those with CHD or stroke.

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