The causal relationship between immune cells and both seropositive and seronegative rheumatoid arthritis: A bidirectional Mendelian randomization study.

ivated and resting CD4 regulatory T cell %CD4 regulatory T cell transitional B cell absolute count, CD39 on CD39 + CD4 + T cell, naive-mature B cell %lymphocyte, and IgD + CD38 dim B cell %B cell, antibody-secreting plasmablasts expressing CD24–CD38 + molecules, [ 44 ] whereas our findings indicate a decreasing trend in cells expressing the CD38 + molecule, which may elucidate the absence of relevant seronegative RA-specific antibodies.

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