highly significantP < 0.01
Values were considered statistically significant at * P < 0.05 and highly significant at ** P < 0.01, *** P < 0.001, and **** P < 0.0001.
Values were considered statistically significant at * P < 0.05 and highly significant at ** P < 0.01, *** P < 0.001, and **** P < 0.0001.