Biological Activity and Structural Biology of Current KAT6A Inhibitor Chemotypes.

J Med Chem · 2026 · PMC12910677 · PMID 41611522

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highly significantno p-value reported

Substitution of the oxazole ring with imidaz-2-yl ( 31 ) led to a highly significant loss of activity (IC 50 = 99 μM).

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