Continuous ketamine infusion for surgical patients in the intensive care unit: a systematic review and meta-analysis of randomized controlled trials with GRADE assessment.

Crit Care · 2026 · PMC12911331 · PMID 41578281

Europe PMC DOI

hedged sentence

0.0500

closest p · 1.0× alpha

0.0500

boldest claim

The sentences

narrowly missed statistical significancep ≈ 0.05actually significant

ICU length of stay was only about 1 h shorter on average with ketamine (mean difference ≈ − 0.97 h) and this trend narrowly missed statistical significance ( p ≈ 0.05).

also in 227 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.