Barely Significant
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<i>Akkermansia muciniphila</i> alleviates experimental colitis through FXR-mediated repression of unspliced XBP1.

mSystems · 2026 · PMC12911386 · PMID 41459926

Europe PMCDOI
1
hedged sentence
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

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marginally significantP = 0.06so close (0.05 < p ≤ 0.1)
Quantitative analysis revealed a marginally significant upward trend in XBP1u expression (1.85-fold, P = 0.06) in our FXR −/− mice compared with wild-type controls, as evidenced by protein immunoblotting.

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