A systems approach identifies MERTK as a therapeutic vulnerability in ZFTA-RELA-driven ependymomas.

Proc Natl Acad Sci U S A · 2026 · PMC12912970 · PMID 41665993

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highly significantP = 3.0 × 10 17a dropped decimal point

These patterns were supported by highly significant overlaps in both upregulated ( P = 3.0 × 10 17 ) and downregulated ( P = 9.6 × 10 48 ) gene sets ( SI Appendix , Fig.

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