In line with these results, immunoblot analysis revealed an increasing trend in the expression of p27 Kip1 following OPE treatment (Fig. 8 B), supporting the possibility that OPE exerts cytostatic effects through modulation of the AMPK/p27 Kip1 axis.
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Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in malignant cells.
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