Integrated multi-omics analysis reveals GPD1L-mediated dysregulation of glycerophospholipid metabolism facilitates the progression of lung adenocarcinoma.

Additionally, the plasma level of Glycero-3-phosphocholine also exhibited a decreasing trend during the tumor progression (Fig. 5 M), suggesting that the plasma glycerophospholipid metabolites may possess similar prognostic utility and could be explored as non-invasive biomarkers for monitoring lung adenocarcinoma progression.

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