In the United States (US), while paramount efforts had been made to prevent all premature births [ 11 ], a slightly increasing trend in PTB has been observed since 2010 according to the national birth data released by the Centers for Disease Control and Prevention (CDC) [ 63 ].
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Associations between prenatal exposure to ambient air pollutants and preterm birth in the Atlanta African American maternal-child cohort.
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On the other hand, the association of PM 2.5 with miPTB was statistically significant during the 2 nd trimester (OR: 1.90, 95%CI: 1.03–3.43) and marginally significant across the entire pregnancy (OR: 2.46, 95%CI:0.98- 6.01).