Decoding the tumor microenvironment remodeling orchestrated by CLEC3B+ inflammatory cancer-associated fibroblasts in lung adenocarcinoma immunotherapy: elucidation from pan-cancer spatially single-cell transcriptomics landscape.

J Transl Med · 2026 · PMC12918745 · PMID 41526921

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highly significantno p-value reported

By employing 113 predictive ML approaches and a LOOCV system, we refined a highly significant model and benchmarked it against existing ICI-related signatures (Fig. 3 A).

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