<i>Saccharomyces boulardii</i> in patients with severe acute pancreatitis: a single center, open-label randomized controlled trial.

Although the within-group comparison did not show a statistical difference ( P = 0.15 in the Control group, P = 0.88 in the Probiotic group), Enterococcus in the gut tended to proliferate in the Control group after 48 h compared to admission to the ICU, while it showed a decreasing trend in the Probiotic group ( Supplement Fig.

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