highly significantp < 0.001
Quantification of signal intensities demonstrated highly significant reductions in tracer binding in both the kidney (−50%, p < 0.001) and pancreas (−32%, p < 0.001) of KO animals, indicating that a large proportion of the [ 18 F]TAAR1-2203 signal in these peripheral organs is attributable to specific TAAR1-mediated binding.