Macrophage-specific N-terminal truncation of Plin2 limits the size of lipid droplets.

Biochem J · 2026 · PMC12921128 · PMID 41527766

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highly significantno p-value reported

The presence of proline (P41) within this motif is highly significant; while proline typically creates a structural barrier for common proteases, specialized enzymes such as prolyl oligopeptidases (POP) specifically cleave the carboxyl side of proline residues [ 22 ].

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