Comparison of Subcutaneous Versus Intramuscular Estradiol Administration for Feminizing Gender-Affirming Hormone Therapy.

Pharmacy (Basel) · 2026 · PMC12922051 · PMID 41718214

Europe PMC DOI

hedged sentence

0.0750

closest p · 1.5× alpha

0.0750

boldest claim

The sentences

a trend toward significancep = 0.075so close (0.05 < p ≤ 0.1)

showed a trendp = 0.075so close (0.05 < p ≤ 0.1)

Estradiol dose showed a trend toward significance (B = 51.86, p = 0.075), suggesting a positive association with serum estradiol.

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