Integrated metagenomic and 16S rRNA analysis reveals temporal associations between resistance genes and microbial communities during dairy manure composting.

Sci Rep · 2026 · PMC12923527 · PMID 41644585

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0010

boldest claim

The sentences

highly significantP < 0.001actually significant

MGEs were also significantly associated with ARGs (M2 = 0.695, P = 0.024) and showed a highly significant correlation with MRGs (M2 = 0.601, P < 0.001).

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an increasing trendno p-value reported

Interestingly, the relative abundance of the sul2 gene within the sulfonamide class showed an increasing trend, which contrasts with the behavior of other types of ARGs.

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a decreasing trendno p-value reported

The majority exhibited a decreasing trend in abundance, including aadD, ant9-I, aad9, dfrA17, ermB, erm36, among others.

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