Codon usage optimization contributes to evolutionary dynamics of TetM following its acquisition via interspecies and intergeneric recombination events in recipient bacteria.

BMC Microbiol · 2026 · PMC12924463 · PMID 41612178

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closest p · 0.0× alpha

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highly significantp < 10−8actually significant

M8) were highly significant (all p < 10−8; Table 3 ), with models M2a and M8 estimating that ~ 4.1% of codons evolve under positive selection (ω ≈ 2.31).

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