Associations Between Right Ventricular Remodeling, Exercise and Circulating Metabolites in Volume and Pressure Overload States.

Although nonfasting serum samples may generate analytic differences due to diet, prior studies suggest that variability in the measurements of most metabolites may not be significant with or without fasting. 53 Lastly, we used rTOF as representative of RV volume overloading state, and such representation has been adopted in previous studies. 7 , 27 , 54 Nevertheless, rTOF is a specific condition, and our findings may not be extrapolated to other RV volume overload states such as atrial septal defect or tricuspid insufficiency.

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