CASPR2 Autoimmune Antibodies Induce Neuronal Hyperactivity in Human Brain Organoids.

J Neurochem · 2026 · PMC12926859 · PMID 41725505

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

a pronounced trendno p-value reported

In terms of intrinsic neuronal membrane properties, capacitance (Cm CTR = 35.84 ± 3.050 pF, n = 25; Cm CASPR2 = 44.60 ± 2.723 pF, n = 45; p = 0.0575) and membrane resistance (Rm CTR = 874.9 ± 108.9 MΩ, n = 25; Rm CASPR2 = 725.5 ± 57.01 MΩ, n = 45; p = 0.2231) were not statistically different between conditions, however, there was a pronounced trend for larger capacitance in neurons from CASPR2‐Ab organoids (Figure 1f,g ).

also in 237 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.