Assessment of the Effectiveness, Tolerability, and Safety of the Preservative-Free Fixed Combination of Timolol, Dorzolamide, and Brimonidine Compared to Separate Therapies in Patients with Glaucoma, a Randomized Controlled Trial.

Clin Ophthalmol · 2026 · PMC12927778 · PMID 41737851

Europe PMC DOI

hedged sentence

0.0440

closest p · 0.9× alpha

0.0440

boldest claim

The sentences

an increasing trendp = 0.044actually significant

In contrast, the TDB-FC group showed an increasing trend, with only 20.8% (5/24) of eyes achieving grade 0 (p = 0.044).

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