<i>CEBPB</i> Expression in Tumor Cells Drives Immune Evasion in Colorectal Cancer via <i>CTLA4</i> Up-regulation in T Cells.

Cancer Commun (Lond) · 2026 · PMC12929812 · PMID 41743630

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an increasing trendno p-value reported

In the flow cytometry analysis of the tumors from immunocompetent mice, compared with EV control tumors, Cebpb -oe tumors had fewer tumor-infiltrating CD4 + T cells, with a higher proportion of CTLA-4 + cells and an increasing trend of Foxp3 + CTLA-4 + cells among CD4 + T cells, whereas Foxp3 − CTLA-4 + cells remained similar among CD4 + T cells (Fig. 7 B, top).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

&lt;i&gt;CEBPB&lt;/i&gt; Expression in Tumor Cells Drives Immune Evasion in Colorectal Cancer via &lt;i&gt;CTLA4&lt;/i&gt; Up-regulation in T Cells.

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<i>CEBPB</i> Expression in Tumor Cells Drives Immune Evasion in Colorectal Cancer via <i>CTLA4</i> Up-regulation in T Cells.