Effectiveness of Lung Cancer Screening by Sex and Tumor Histology: Extended, Pooled Analysis of the ITALUNG and LUSI Trials, with Comparison to Findings in the NLST.

Cancer Commun (Lond) · 2026 · PMC12929912 · PMID 41743631

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borderline significantno p-value reported

For women only, NLST showed an additional, borderline significant mortality risk reduction (hazard ratio [HR] = 0.67; 95% confidence interval [CI]: 0.40 to 1.03) for small-cell LC (SCLC), which, however, was deemed a possible chance observation [ 1 ].

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