Intermolecular Stacking-Instructed Chiral Preference in Covalent 2 + 2 Macrocyclization.

JACS Au · 2026 · PMC12933336 · PMID 41755864

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an interesting trendno p-value reported

Overall, these results demonstrate an interesting trend that L,L,D,D- and L,D,D,L-macrocycles, the preferentially formed products, have centrosymmetric conformations in the solid state.

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