Despite not reaching the conservative whole-brain level threshold for significance, we considered these prefrontal clusters of interest, because they overlap with those exhibiting highly significant dopamine-dependent methylphenidate effects on RPE signaling, as revealed by a previous univariate fMRI analyses of this dataset ( van den Bosch et al., 2022 ).
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Validating molecular target-enriched fMRI for disentangling drug effects on dopamine.
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