Adverse reactions following first three doses of the BNT162b2 mRNA COVID-19 vaccine: A prospective cohort study on relationships with individual characteristics and previous experience of adverse reactions.

Across the three doses, no consistent pattern was observed in adjusted RR based on individual characteristics. Participants with previous moderate or severe systemic adverse reactions following the second and third doses had a higher adjusted RR for moderate or severe systemic reactions with at least a marginal significance (1.31 [0.99–1.72] for the second dose, 2.18 [1.56–3.06] for the third dose).

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