a statistical trendP = 0.0777
Moreover, the model showed a time‐dependent change of Cyclin E expression ratios to 6 h ( P = 0.0132) and a statistical trend to difference between 6 and 9 h ( P = 0.0777) in nonresponders while expression ratios in responders remained close to baseline at all time points. 3.4 BrdU incorporation predicts opposite responses and indicates altered TTSP in HCC patients undergoing HDR ‐ BT Relative to BrdU incorporation ratios, Receiver Operating Characteristics yielded an AUC of 0.80 for Huh7 and 0.89 for HepG2 to distinguish between responders and nonresponders, respectively (Fig. 5A,B ).