Targeted expression of the immunomodulatory peptide Scy by engineered <i>Escherichia coli</i> Nissle 1917 for alleviating enterotoxigenic <i>E. coli</i> infection.

Front Immunol · 2026 · PMC12936861 · PMID 41766863

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a decreasing trendno p-value reported

3.5 Modulatory effects of EcN-Scy on gut microbiota composition in mice 16S rDNA sequencing revealed that Chao, Shannon, and Sobs indices showed a decreasing trend following intervention with both EcN and EcN-Scy, indicating reduced microbial richness and evenness ( Figure 5A ).

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Targeted expression of the immunomodulatory peptide Scy by engineered &lt;i&gt;Escherichia coli&lt;/i&gt; Nissle 1917 for alleviating enterotoxigenic &lt;i&gt;E. coli&lt;/i&gt; infection.

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Targeted expression of the immunomodulatory peptide Scy by engineered <i>Escherichia coli</i> Nissle 1917 for alleviating enterotoxigenic <i>E. coli</i> infection.