Barely Significant
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Impact of Right Ventricular Pacing Sites on Right Ventricular Function: Systematic Review and Meta-analysis.

Arrhythm Electrophysiol Rev · 2026 · PMC12937077 · PMID 41769198

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The sentences

highly significantp≤0.001actually significant
showed that restoration of AV synchrony with atrial and AV sequential pacing resulted in a highly significant (p≤0.001) increase in systolic blood pressure, cardiac output and stroke volume. 57 In another study, Abraham et al. found that in two patients with clinical evidence of RV infarction, atrial and AV sequential pacing resulted in immediate and sustained improvement in systolic blood pressure and clinical indices of perfusion. 58 Although these two studies are small, the findings may show benefit in settings of acute decompensation of the RV by enhancing RV function and, in turn, cardiac output.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.