Let-7a and miR-34a Interplay Potent Suppressive Roles in Hepatocellular Carcinoma via Co-Targeting FNDC3B, IGF2 and SOX4.

Int J Mol Sci · 2026 · PMC12940684 · PMID 41751849

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highly significantno p-value reported

HCC Cell Line Propagation HepG2 was selected as the HCC cell culture model because it attains the major malignant properties of HCC and the two miRs of interest showed highly significant down expression in these cells.

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Let-7a and miR-34a Interplay Potent Suppressive Roles in Hepatocellular Carcinoma via Co-Targeting &lt;i&gt;FNDC3B&lt;/i&gt;, &lt;i&gt;IGF2&lt;/i&gt; and &lt;i&gt;SOX4&lt;/i&gt;.

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Let-7a and miR-34a Interplay Potent Suppressive Roles in Hepatocellular Carcinoma via Co-Targeting <i>FNDC3B</i>, <i>IGF2</i> and <i>SOX4</i>.