Barely Significant
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Integrating Genomic and Clinical Data in AML: Real-World Application of the Sanger Multistage Model.

Genes (Basel) · 2026 · PMC12941301 · PMID 41751601

Europe PMCDOI
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highly significantp < 0.0001actually significant
The overall model was highly significant (Chi-square = 29.88, df = 6, p < 0.0001) with good discriminative ability (Harrell’s C-index 0.732, 95% CI 0.660–0.804), indicating how TP53 mutation is the predominant independent factor influencing outcome.

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