Untargeted Metabolomics of Human Airway Epithelium Reveals Neuroactive Signatures Linked to Pulmonary Neuroendocrine Cell Enrichment and Allergen Exposure.

Metabolites · 2026 · PMC12942826 · PMID 41745618

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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extremely significantp = 7.0 × 10 −93actually significant

HBEC + HDM) was extremely significant for both up-regulated ( p = 7.0 × 10 −93 ) and down-regulated metabolites ( p = 2.8 × 10 −49 ), indicating that core metabolic distinctions between ePNECs and HBECs are strongly preserved following allergen exposure.

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