Nanostructured Lipid Carriers Containing Norfloxacin and 2-Aminothiophene Derivative Reduces Fluoroquinolone Resistance in Multidrug-Resistant <i>Staphylococcus aureus</i> Strains by Efflux Pump Inhibition.

In contrast to the formulations of 0.5% and 1.0% of Tween ® , the formulation with 3.0% concentration resulted in a highly significant increase in these parameters, as well as phase separation of the formulation, indicating that excess of Tween ® negatively affected the stability of the system.

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