Dapagliflozin mitigates myocardial inflammation and metabolic stress in heart failure through STAT1 inhibition: Evidence from multi-omics analyses and experimental exploration.

PLoS One · 2026 · PMC12948057 · PMID 41758878

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an increasing trendno p-value reported

Comparison of macrophage subsets across clinical groups ( Fig 7G ) indicated that M0 cell proportions were relatively stable, while the M1 population showed an increasing trend in DCM and ICM (both infarcted and non-infarcted regions).

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