Significant Production of Serum and Mucosal Anti-Spike-IgA Antibodies After Vaccine-Encoded or SARS-CoV-2-Infection-Induced Spike-Exposures in Patients with Asthma Treated with Monoclonal Antibodies Compared to Conventional Therapy.

J Asthma Allergy · 2026 · PMC12949803 · PMID 41773183

Europe PMC DOI

hedged sentence

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

near to significancep=0.058so close (0.05 < p ≤ 0.1)

However, in the 9 individuals of the conv group as well as in the 9 treated individuals receiving mAb, BMI positively correlated with nasal anti-S1-IgA and nasal anti-RBD IgG antibodies ( Supplementary Figure 4B and Supplementary Table 11 ), with IC50 against Wuhan-type SARS-CoV-2 and near to significance with anti-spike-IgG concentrations (p=0.058).

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