European Registry on <i>Helicobacter pylori</i> Management (Hp-EuReg): Most relevant results for clinical practice.

When the 2013–2016 period was compared to 2017–2020, all antibiotics’ primary resistance rates showed a decreasing trend, but a greater significant decrease was observed in the metronidazole resistance rate between the same periods (33% and 24%, p < 0.001; respectively), as it is likewise reported in Figure 8 , updated in April 2022, where the evolution of all antibiotics’ prevalence is reported and where the metronidazole prevalence is currently still decreasing.

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