Medial prefrontal cortical neurotransmitters reactive to relapse-promoting and relapse-suppressing cues in male rats trained to self-administer cocaine or alcohol.

Addict Neurosci · 2026 · PMC12952761 · PMID 41777724

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0.0900

closest p · 1.8× alpha

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almost significantp = 0.09so close (0.05 < p ≤ 0.1)

In IL of alcohol-trained rats ( Table 5 ), ANOVA revealed significant effects of Cue ( p < 0.05) and almost significant Cue × Time interaction ( p = 0.09) for glutamate, significant Cue × Time interaction ( p < 0.05) for dopamine ( Fig. 3F ), significant effect of Cue ( p < 0.05) and Cue × Time interaction ( p < 0.05) for GABA ( Fig. 3H ), and significant effect of Time ( p < 0.05) for aspartate ( Fig. 3L ).

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