Comparative Efficacy and Safety of Non-Clotting Factor Prophylaxis Versus. on-Demand Therapy in Hemophilia: A Meta-Analysis of Randomized Controlled Trials.

Clin Appl Thromb Hemost · 2026 · PMC12957592 · PMID 41773617

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a favorable trendno p-value reported

The results indicated a favorable trend for prophylaxis, with a significantly lower joint ABR found in the intervention group [RR = 0.09; 95% CI: (0.06, 0.14)] as compared to the control group.

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