Barely Significant
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Global, Regional, and National Burden of Breast Cancer Attributable to Low Physical Activity in Women of Reproductive Age: Historical Trends from 1990 to 2021 and Projections to 2035.

Arch Iran Med · 2025 · PMC12958434 · PMID 41778434

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an increasing trendno p-value reported
Conclusion: Globally, the burden of breast cancer in women of reproductive age attributable to LPA has shown an increasing trend, with significant regional disparities.

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a decreasing trendno p-value reported
Results: From 1990 to 2021, in high sociodemographic index (SDI) regions, deaths and disability-adjusted life years (DALYs) of breast cancer in women of reproductive age attributable to LPA showed a decreasing trend, with corresponding estimated annual percentage change (EAPC) values of -1.20 (95% CI: -1.29, -1.10) and -1.05 (95% CI: -1.14, -0.96), respectively.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.