Strong constitutive NF-κB signaling in B cells drives SLL/CLL-like lymphomagenesis and overcomes microenvironmental dependencies.

Leukemia · 2026 · PMC12960208 · PMID 41545700

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a slight trendno p-value reported

Moreover, Ki-67 staining by immunohistochemistry revealed varying levels of proliferative activity within the CLL-like lymphomas, ranging from 5–50%, with a slight trend towards increased proportions of Ki-67 + cells when canonical NF-κB is activated (Figs. 4A and S4F ).

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