highly significantP -value < 0.001
Interestingly, pairing with different minPs had highly significant effects on both the promoter and enhancer activities of tested elements (Promoter activity, F(2, 8301) = 457.7, P -value < 0.001, ANOVA; Enhancer activity, F(2, 8296) = 309.5, P -value < 0.001; Fig. 6a, b).